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Monday, March 3, 2008


A Computer Program Designed for Clinical Pharmacokinetic (CPK) Services (or Therapeutic Drug Monitoring, TDM)

mobilePK (formerly JavaPK for Mobiles) is a clinical pharmacokinetic (or therapeutic drug monitoring, TDM) tool for mobile devices including PalmOS v5 PDA phones (Tréo series, p/w), Symbian OS Java-supported mobile phones or smartphones (incl. Motorola, Nokia, BlackBerry and Sony Ericsson), and Pocket PCs or smartphones (WM2003/WM5/WM6). mobilePK was written in Java (Java ME, JDK v6.0 with NetBeans IDE v6), and was the first clinical pharmacokinetic program in the world running on mobile phones (with MIDP v2.0 and CLDC v1.0 or above).

It was built with Sawchuk-Zaske method (aminoglycosides and vancomycin), Chiou method (theophylline iv inf.) and Bayesian estimation method (gentamicin, tobramyin, amikacin, vancomycin, digoxin, phenytoin, cyclosporin-A, lithium, carbamazepine, theophylline and warfarin). With Bayesian estimation, one can use only one blood sample (at steady-state) to estimate individual pharmacokinetic parameters at steady-state. And now we are have a similar program running different platforms running on Mac OS X, WinXP Desktop PC, and Linux-based PC (Fedora Core 3/4/5).


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